there aren't really any spoilers in it. I just posted that link because everthing prior to it has pretty much just showed off combat. and since most of those focused on protecting a little sister while she was harvesting, they kind of give the wrong impression that the game is going to be more shooter with constant re-spawning of splicers.
I kind of bought into the hype with the first bioshock, so I'm going to take a wait and see approach. but that clip, along with the behavior and look of the little sisters in this http://www.youtube.com/watch?v=Q1-HK5LImgA&feature=fvsr video gives me a little more hope for a decent game then I had when it was anounced you'd play as a "prototype" big daddy.
granted, that's multiplayer, but it looks like the little sisters will be more like they originally were in the first bioshock. before they changed them.