he blamed vaccinated people “shedding” onto him.
Some research on Long Covid in the brain:
https://qbi.uq.edu.au/article/2023/0...8fuse%E2%80%99
Researchers at The University of Queensland have discovered viruses such as SARS-CoV-2 can cause brain cells to fuse, initiating malfunctions that lead to chronic neurological symptoms.
...
SARS-CoV-2, the virus that causes COVID-19, has been detected in the brains of people with ‘long COVID’ months after their initial infection.
“We discovered COVID-19 causes neurons to undergo a cell fusion process, which has not been seen before,” Professor Hilliard said.
“After neuronal infection with SARS-CoV-2, the spike S protein becomes present in neurons, and once neurons fuse, they don’t die.”
“They either start firing synchronously, or they stop functioning altogether.”
As an analogy, Professor Hilliard likened the role of neurons to that of wires connecting switches to the lights in a kitchen and a bathroom.
“Once fusion takes place, each switch either turns on both the kitchen and bathroom lights at the same time, or neither of them,” he said.
“It’s bad news for the two independent circuits.”
The discovery offers a potential explanation for persistent neurological effects after a viral infection.
“In the current understanding of what happens when a virus enters the brain, there are two outcomes – either cell death or inflammation,” Dr Martinez-Marmol said.
“But we’ve shown a third possible outcome, which is neuronal fusion.”
Dr Martinez-Marmol said numerous viruses cause cell fusion in other tissues, but also infect the nervous system and could be causing the same problem there.
“These viruses include HIV, rabies, Japanese encephalitis, measles, herpes simplex virus and Zika virus,” he said.
“Our research reveals a new mechanism for the neurological events that happen during a viral infection.
“This is potentially a major cause of neurological diseases and clinical symptoms that is still unexplored.”
Mimicrying the herpes in the brain is a good interpretation......persistent subclinical symptoms
An acquaintance of mine is an anti vaxxer, obviously never vaccinated. She got infected 5 times, and had heart palpitations for a few months (which she dismissed as stress). Ran into her last week, and she's completely fine now. Granted, she's only 35 but still. You never know what this virus will do or not do
I had a bad spate of the ole heart palps in April and early May. They're annoying in that they basically wreck the entire day trying to get things done. But the worst part is they have to keep reminding me of my mortality in little flashes during the brief bad spells -- like sudden flashes of surprise! Time's up! Never mind that little music project you don't get to finish this weekend. It's over. Eternal darkness, and there is literally nothing you can do in another week or 50 more years that gonna hold a candle against the vast darkness of eternity on the other side...* Really dark & foreboding thoughts I'd never really had that's maybe special about heart issues that's different than say, a skinned knee or twisted ankle, even though the latter hurts a lot worse. (My cardiologist keeps reassuring me there's nothing life or even health-threatening about them, aside from the exhaustion, but it's still scary to sit through a spell. Edit: Echocardiogram & x-ray verified in case lowenz was wondering.)
Around the end of May I started running every weekday, and that's seemed to had a good effect, anecdotally as that is, and I'm feeling great these days. I mean as far as one can after they've looked deep into the abyss and then backed away to find themselves at some luncheon with neighbors in somebody's garden with people talking about the latest thunderstorm cell that just missed us or how they need to get the oil changed in their car soon, and what even is this world anymore? I hate this disease.
* I don't think eternal darkness is the right concept since I've come to think multiverse theory (i.e., Eternal Inflation theory, and eternal re-occurance along with it) is, well, I wouldn't say I know indisputably that it's right, but it's the outcome I'd bet on right now and the physicists I like and respect the most, like Lenny Susskind, are on board with it. And it's gonna offer a much different vision of life and death in the cosmic scheme of things. But that's gotta be for another post! Of course, being human, it's hard to stave off dark thoughts creeping in no matter what one believes, I think.
Last edited by demagogue; 16th Jun 2023 at 18:52.
"completely fine" without an echocardiogram is just a wishOriginally Posted by Azaran
Yeah, should have clarified she feels and looks fine, but who knows what's going on inside"completely fine" without an echocardiogram is just a wish
Laura Loomer upset that they did something to the food because everything tastes and smells weird now.
For context she's the woman who chained herself to the door at Twitter that one time, and is an anti-vaxxer who ended up with a brutal bout of Covid late last year after downplaying the severity of the disease.
She basically just doxxed herself right now as having severe Long Covid symptoms, which she is in denial about.
Effects of Vaccines on the Sequelae Rates of Recurrent Infections and the Severity of Pulmonary COVID-19 Infection by Imaging
The major findings of our study were: (1) sequelae were frequently observed in unvaccinated cases; (2) the correlation between vaccination status and the severity of sequelae was significant; (3) there was not any significant relationship between the vaccine type and the severity of sequelae; and (4) hematocrit, hemoglobin, and lymphocyte parameters may be used as predictors of sequelae rates. COVID-19 infection, although reduced in prevalence following the development of vaccines, still remains a public health concern because of reinfection. Vaccination not only appears to protect against primary infection, but also seems to reduce reinfection and sequalae rates following reinfection.
https://edition.cnn.com/2023/08/18/h...ess/index.html
tl;dr is that they saw a stronger immune response weeks later, when both shots were in the same arm, 67% of recipients had detectable "killer T cells" vs only 43% who got shots in alternating arms.Which arm gets the Covid-19 booster may make a difference, study shows
This is something where there's basically no literature or study with other vaccines, since pretty much nobody has thought to check that before. If it pans out as having a measurable impact on protection, even if small, it could change how we advise on many vaccines and not just Covid.
That's strange :|
The immune response activating only locally. Well, T killers is only a part of the immune response (and the one that can stop the infection from the start) where antibodies produced by B cell act as a containment/control strategy
From the article:
It makes sense why the location of the injection would make a difference, Schaffner added.
The cells that provide the immune response are in local lymph nodes, he said.
Lymph nodes are across the body in places including the neck, chest, abdomen and armpits, according to the American Cancer Society.
If the immune cells in those lymph nodes are restimulated in the same place, there is a greater immunological response, the study said.They also said that the antibodies were more effective at binding to the spike proteins when the injection was in the same arm, but they didn't find "more" antibodies. So even if antibody levels aren't higher there seem to be quality factors involved too.
Last edited by Cipheron; 19th Aug 2023 at 03:29. Reason: Typos
My guess would be tissue resident memory cells driving faster / stronger cellular ramp-ups during re-challenge.
A new study adds additional credibility to zinc as a Covid treatment
The study found that 30-day mortality was 6.5% in the zinc group compared to 9.2% in the placebo group—despite similar severity of illness between the two groups. The ICU admission rate was 5.2% in the zinc group and 11.3% in the placebo group. The trial also found evidence of a treatment positive effect with zinc, as compared with placebo, in inpatients, patients older than 65, patients with a comorbidity, and those requiring oxygen at baseline. Among outpatients, the duration of COVID-19 symptoms was found to be shorter in the zinc group. The rate of hospital admission was similar between both the patients treated with zinc and those given placebo. There was no significant difference in rates of adverse events between the two groups.
There are articles stating that people with a zinc deficiency have worse Covid outcomes.
This would neatly explain why some studies say zinc does nothing while others find it had a good effect. It depends on where you do the study if you're not actually controlling for zinc deficiency levels.
How i read the overall results is that people who NEED the zinc can benefit from it, but there's no actual evidence that just giving zinc to everyone will help.
https://www.sciencedirect.com/scienc...0197122030730X
Patients with coronavirus disease 2019 (COVID-19) had significantly low zinc levels in comparison to healthy controls.
Zinc deficient patients developed more complications (70.4% vs 30.0%, p = 0.009).
Zinc deficient COVID-19 patients had a prolonged hospital stay (7.9 vs 5.7 days, p = 0.048).
In vitro studies have shown that reduced zinc levels favour the interaction of angiotensin-converting enzyme 2 (ACE2) with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein and likewise that increased zinc levels inhibit ACE2 expression resulting in reduced viral interaction.
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